Effects of trabecular type and orientation on microdamage susceptibility in trabecular bone
نویسندگان
چکیده
منابع مشابه
Determinants of Microdamage in Elderly Human Vertebral Trabecular Bone
Previous studies have shown that microdamage accumulates in bone as a result of physiological loading and occurs naturally in human trabecular bone. The purpose of this study was to determine the factors associated with pre-existing microdamage in human vertebral trabecular bone, namely age, architecture, hardness, mineral and organic matrix. Trabecular bone cores were collected from human L2 v...
متن کاملTrabecular bone microdamage and microstructural stresses under uniaxial compression.
The balance between local remodeling and accumulation of trabecular bone microdamage is believed to play an important role in the maintenance of skeletal integrity. However, the local mechanical parameters associated with microdamage initiation are not well understood. Using histological damage labeling, micro-CT imaging, and image-based finite element analysis, regions of trabecular bone micro...
متن کاملMicroarchitecture Influences Microdamage Accumulation in Human Vertebral Trabecular Bone
It has been suggested that accumulation of microdamage with age contributes to skeletal fragility. However, data on the age-related increase in microdamage and the association between microdamage and trabecular microarchitecture in human vertebral cancellous bone are limited. We quantified microdamage in cancellous bone from human lumbar (L(2)) vertebral bodies obtained from 23 donors 54-93 yr ...
متن کاملDetection of trabecular bone microdamage by micro-computed tomography.
Microdamage is an important component of bone quality and affects bone remodeling. Improved techniques to assess microdamage without the need for histological sectioning would provide insight into the role of microdamage in trabecular bone strength by allowing the spatial distribution of damage within the trabecular microstructure to be measured. Nineteen cylindrical trabecular bone specimens w...
متن کاملA theoretical analysis of long-term bisphosphonate effects on trabecular bone volume and microdamage.
Bisphosphonates increase bone mass and reduce fracture risk, but their anti-resorptive action may lead to increases in fatigue microdamage. To investigate how bisphosphonate effects influence changes in bone volume and microdamage in the long term, a strain-adaptive model of bone remodeling and microdamage balance was developed for a continuum-level volume of postmenopausal trabecular bone by i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bone
سال: 2010
ISSN: 8756-3282
DOI: 10.1016/j.bone.2010.02.005